OTHER NAMES(S): Abricot Argent Japonais, Adiantifolia, Arbre aux, OTHER NAME(S): Abricot Argent Japonais, Adiantifolia, Arbre aux. J Psychiatry Neurosci 2001;26:221-8. Ginkgo biloba is available in various forms such as liquid extracts, tablets, capsules, and dried leaves/tea. Ginkgo biloba extract (EGb761) influences monoaminergic neurotransmission via inhibition of NE uptake, but not MAO activity after chronic treatment. Med J Aust 2006;184:583-4. Trick, L., Boyle, J., and Hindmarch, I. Stevens-Johnson syndrome with Ginkgo biloba. Pharmacopsychiatry 2010;43(3):86-91. Speak with a healthcare provider to find out what dose might be best for a specific condition. Curr Med Res Opin 2008;24(2):591-599. BMC Complement Altern Med 2011;11:21. Acute hemolytic anemia in glucose-6-phosphate dehydrogenase deficiency complicated by Ginkgo biloba. Chen X, Hong Y, Zheng P. Efficacy and safety of extract of Ginkgo biloba as an adjunct therapy in chronic schizophrenia: A systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. Aging Ment.Health 2009;13(2):183-190. Effects of Ginkgo biloba extract EGb 761 on neuropsychiatric symptoms of dementia: findings from a randomised controlled trial. View abstract. A preliminary, double-blind versus placebo study]. View abstract. Thomas, M., Sheran, J., Smith, N., Fonseca, S., and Lee, A. J. AKL1, a botanical mixture for the treatment of asthma: a randomised, double-blind, placebo-controlled, cross-over study. Nicolai, S. P., Gerardu, V. C., Kruidenier, L. M., Prins, M. H., and Teijink, J. J Ethnopharmacol 2000;71:83-8. View abstract. Xing X, Kong M, Hou Q, Li J, Qian W, Chen X, Li H, Yang C. Effects of ginkgo leaf tablet on the pharmacokinetics of rosiglitazone in rats and its potential mechanism. Burkard G. [The efficacy and safety of ginkgo biloba extract in dementia]. Cytotoxicity of alkylphenols from Ginkgo biloba. Kellermann AJ, Kloft C. Is there a risk of bleeding associated with standardized ginkgo biloba extract therapy? J Neurol Neurosurg Psychiatry 2000;68:679-80. Yoshitake T, Yoshitake S, Kehr J. The efficacy of Egb 761 in patients with senile dementia of the Alzheimer type, A double-blind, placebo-controlled study on different levels of investigation. Does Ginkgo Biloba interact with any drugs? It seems to improve blood circulation, and might also act as an antioxidant to slow down changes in the brain. Cochrane Database Syst Rev 2007;(2):CD003120. Laws, K. R., Sweetnam, H., and Kondel, T. K. Is Ginkgo biloba a cognitive enhancer in healthy individuals? View abstract. 2010;23(5):528-533. The ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid. Kudolo GB, Wang W, Elrod R, et al. Effect of Ginkgo biloba on visual field and contrast sensitivity in Chinese patients with normal tension glaucoma: a randomized, crossover clinical trial. View abstract. View abstract. Leptin Hormone & Supplements: Do They Work for Obesity & Weight Loss? View abstract. Acute generalised exanthematous pustulosis induced by the herbal remedy Ginkgo biloba. View abstract. Front Nutr 2021;8:658630. Ginkbilobin, a novel antifungal protein from Ginkgo biloba seeds with sequence similarity to embryo-abundant protein. View abstract. Arenz A, Kelin M, Flehe K, et al. Clin Nutr 2006;25:606-16. Ginkgo Biloba has also been used to treat seasonal affective disorder, age-related memory loss, asthma, tinnitus (ringing in the ears), high blood pressure, multiple sclerosis, cocaine addiction, or sexual problems caused by taking antidepressants. Forstl H. Clinical issues in current drug therapy for dementia. View abstract. It is not certain whether Ginkgo Biloba is effective in treating any medical condition. III. Penzak, S. R., Busse, K. H., Robertson, S. M., Formentini, E., Alfaro, R. M., and Davey, R. T., Jr. What is this medication? Ginkgo might slow blood clotting. J Assist Reprod Genet 1999;16:87-91. Mix JA, Crews WD. A double-blind, placebo-controlled trial of extract of Ginkgo biloba added to haloperidol in treatment-resistant patients with schizophrenia. Zhu, L., Gao, J., Wang, Y., Zhao, X. N., and Zhang, Z. X. Neuron degeneration induced by verapamil and attenuated by EGb761. Meta-analysis of 11 clinical studies in patients with cerebrovascular insufficiency in old age]. [Effects of Ginkgo biloba extract on 2 models of experimental myocardial ischemia]. Phytother Res 2020 Oct 8. doi: 10.1002/ptr.6822. White HL, Scates PW, Cooper BR. Wesnes K, Simmons D, Rook M, Simpson P. A double-blind placebo-controlled trial of Tanakan in the treatment of idiopathic cognitive impairment in the elderly. Health Benefits Possibly Effective for: 1) Brain Function Healthy People In 4 trials on over 200 healthy young volunteers, ginkgo extract improved sustained attention (but not speed of attention), pattern recognition, and performance in subtraction tasks. Complement Ther Clin Pract. Mix JA, Crews WD Jr. An examination of the efficacy of Ginkgo biloba extract EGb761 on the neuropsychologic functioning of cognitively intact older adults. Human Psychopharmacol 1987;2:159-69. Wheatley D. Triple-blind, placebo-controlled trial of Ginkgo biloba in sexual dysfunction due to antidepressant drugs. Research: A 2008 review published in the British Journal of Clinical Pharmacology found that red ginseng was often more effective than placebo when reducing ED symptoms. Neurol.Sci 9-25-2010; View abstract. View abstract. Russo, V., Rago, A., Russo, G. M., Calabro, R., and Nigro, G. Ginkgo biloba: an ancient tree with new arrhythmic side effects. View abstract. The acute nootropic effects of Ginkgo biloba in healthy older human subjects: a preliminary investigation. Medicine (Baltimore) 2020;99(2):e18568. The effects of acute doses of standardized Ginkgo biloba extract on memory and psychomotor performance in volunteers. Postgrad Med J 2003;79:531-2.. View abstract. Wiegman DJ, Brinkman K, Franssen EJ. Fatal intracerebral mass bleeding associated with Ginkgo biloba and ibuprofen. 2012;11(10):851-859. One theory is that it influences hormones responsible for achieving an erection. View abstract. View abstract. Ginkgo Biloba seeds are possibly unsafe when taken by mouth after roasting them. Zhao S, Zheng H, Du Y, et al. Rowin J, Lewis SL. [Multicenter, randomized, double-blind drug vs. placebo study of the treatment of tinnitus with Ginkgo biloba extract]. 2009;28(5):553-559. View abstract. Gardiner P, Wornham W. Recent review of complementary and alternative medicine used by adolescents. Di Franco R, Sammarco E, Calvanese MG, De Natale F, Falivene S, Di Lecce A, Giugliano FM, Murino P, Manzo R, Cappabianca S, Muto P, Ravo V. Preventing the acute skin side effects in patients treated with radiotherapy for breast cancer: the use of corneometry in order to evaluate the protective effect of moisturizing creams. Epilepsia 2001;42:280-1. There are many medications, lifestyle changes, and even counseling that could help a man reduce the incidence of ED. Medically reviewed by Drugs.com on Mar 21, 2023. Kudolo GB, Wang W, Javors M, Blodgett J. There is no standard dose of ginkgo biloba supplements. Am J Hematol 2005;79:343-4. Brain Behav. Herrschaft, H., Nacu, A., Likhachev, S., Sholomov, I., Hoerr, R., and Schlaefke, S. Ginkgo biloba extract EGb 761(R) in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg. J Psychiatr.Res 2012;46(6):716-723. A randomized, placebo-controlled, trial. Parsad, D., Pandhi, R., and Juneja, A. J Clin Pharmacol 2008;48(6):671-680. View abstract. Another 2012 study involved the use of ginkgo biloba in glaucoma patients. Kennedy DO, Scholey AB, Wesnes KA. Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9. These effects may translate into some benefits for certain medical problems, but the results have been mixed. J Pharm Health Care Sci. Choi, W. S., Choi, C. J., Kim, K. S., Lee, J. H., Song, C. H., Chung, J. H., Ock, S. M., Lee, J. Aruna D, Naidu MU. Eur J Pharmacol 5-19-1989;164(2):293-302. Support Care Cancer 2013;21(4):1185-92. Inhibition of human cytochromes P450 by components of Ginkgo biloba. Generic name: ginkgo [GINK-goe] Meyer B. Scripnikov, A., Khomenko, A., and Napryeyenko, O. March 2013. Evid.Based.Complement Alternat.Med. Bebbington A, Kulkarni R, Roberts P. Ginkgo biloba: Persistent bleeding after total hip arthroplasty caused by herbal self-medication. Li AL, Shi YD, Landsmann B, et al. View abstract. Since then, other research has shown inconsistent results, with one report in 2012 suggesting that DHEA does not help ED. Ginkgo leaf extract is also used in foods . Before taking ginkgo, talk to your healthcare provider if you are taking ibuprofen. Skogh, M. Extracts of Ginkgo biloba and bleeding or haemorrhage. It's not clear if this is a big concern. Ginkgo might increase the effects of trazodone. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Shindel, A. W., Xin, Z.-C., Lin, G., Fandel, T. M., Huang, Y.-C., Banie, L., Lue, T. F. (2010, February 5). View abstract. Ginkgo Biloba is often sold as an herbal supplement. Clin Neuropharmacol. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. After two years of taking 160mg daily, visual function improved. Available at: www.clinicaltrials.gov/ct/gui/c/r (Accessed 15 June 2000). Matthews, MK. J Clin Pharmacol 2000;40:647-54. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. Many potential causes of ED exist. JAMA 2002;288:835-40. Effect of Western medicine therapy assisted by Ginkgo biloba tablet on vascular cognitive impairment of none dementia. View abstract. For thousands of years, leaves from the Ginkgo biloba tree have been a common treatment in Chinese medicine. Hofferberth B. J Neurol Sci 2010;299:184-7. The management of erectile dysfunction. J Int Med Res 1995;23(1):1-8. Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants. Potential interactions between alternative therapies and warfarin. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Follow all directions on the product label and package. 2011;20(6):508-517. 2022;43(4):152-62. View abstract. People take ginkgo biloba for a range of purposes. Phytomedicine 1999;6:281-3. J Clin Epidemiol. Ginkgo might increase the risk of seizures in some people. Arzneimittelforschung 1999;49(12):1030-1034. Kim, T. E., Kim, B. H., Kim, J., Kim, K. P., Yi, S., Shin, H. S., Lee, Y. O., Lee, K. H., Shin, S. G., Jang, I. J., and Yu, K. S. Comparison of the pharmacokinetics of ticlopidine between administration of a combined fixed-dose tablet formulation of ticlopidine 250 mg/ginkgo extract 80 mg, and concomitant administration of ticlopidine 250-mg and ginkgo extract 80-mg tablets: an open-label, two-treatment, single-dose, randomized-sequence crossover study in healthy Korean male volunteers. Zheng Y, Xie Y, Qi M, et al. Acta Psychiatr Scand 1999;100:62-6. (2016, January 17). Yakoot M, Salem A, Helmy S. Effect of Memo, a natural formula combination, on Mini-Mental State Examination scores in patients with mild cognitive impairment. Wesnes KA, Ward T, McGinty A, Petrini O. Biosci Rep 2020;40(3):BSR20200099. J Clin Pharm Ther. WebMD does not provide medical advice, diagnosis or treatment. Shannon M, McElroy EA, Liebelt EL. View abstract. Si X, Yu Z, Ren X, Huang L, Feng Y. Efficacy and safety of standardized Ginkgo biloba L. leaves extract as an adjuvant therapy for sudden sensorineural hearing loss: A systematic review and meta-analysis. Wien.Med Wochenschr. Benjamin J, Muir T, Briggs K, Pentland B. Transpl Int 2002;15:377-9. Mult.Scler. Presse Med 1986;15:1569-72. Ginkgo biloba-containing products and the risk of cardiac arrhythmias. Arch Sex Behav 2008;37:530-47. Szabo, M. E., Droy-Lefaix, M. T., and Doly, M. Direct measurement of free radicals in ischemic/reperfused diabetic rat retina. This supplement is not intended to diagnose, treat, cure, or prevent any disease. View abstract. We avoid using tertiary references. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Naccarato M, Yoong D, Gough K. A potential drug-herbal interaction between Ginkgo biloba and efavirenz. View abstract. You can email the site owner to let them know you were blocked. Ji H, Zhang G, Yue F, Zhou X. These include: Achieving and maintaining an erection requires several things to happen. Call your doctor for medical advice about side effects. View abstract. Reiter, W. J., Pycha, A., Schatzl, G., Pokorny, A., Gruber, D. M., Huber, J. C., & Marberger, M. (1999, March). Zhong Yao Cai 2002;25:651-3. J AOAC Int. Gurley BJ, Gardner SF, Hubbard MA. Guillon, J. M., Rochette, L., and Baranes, J. Clin Ther 2009;31(10):2249-2257. View abstract. 1 It may also help maintain memory with age decline and improve quality of life in mild dementia. Tan MS, Yu JT, Tan CC, et al. Savaskan E, Mueller H, Hoerr R, von Gunten A, Gauthier S. Treatment effects of Ginkgo biloba extract EGb 761 on the spectrum of behavioral and psychological symptoms of dementia: meta-analysis of randomized controlled trials. Viagra Alternatives: Pills, Natural Remedies, and Over-the-Counter Options, heart and blood pressure-related conditions, history of injury to the penis or surrounding organs. Amri H, Ogwuegbu SO, Boujrad N, et al. 2004;27(12):2042-2045. Mousavi SN, Hosseinikia M, Yousefi Rad E, Saboori S. Beneficial effects of Ginkgo biloba leaf extract on inflammatory markers: A systematic review and meta-analysis of the clinical trials. J Ethnopharmacol 2022;282:114587. 2017 Jan;28(1):4-15. Kajiyama Y, Fujii K, Takeuchi H, Manabe Y. Ginkgo seed poisoning. The Truth Behind the Top 10 Dietary Supplements. Aging Clin Exp Res. Some herbs may interact with medications taken, so anyone considering taking herbs should talk to a doctor or pharmacist about potential problems. Szabo, M. E., Droy-Lefaix, M. T., and Doly, M. EGb 761 and the recovery of ion imbalance in ischemic reperfused diabetic rat retina. View abstract. Phytother.Res 2010;24(3):445-450. View abstract. Ginkgo biloba: evaluation of CYP2C9 drug interactions in vitro and in vivo. Ihl R, Tribanek M, Bachinskaya N. Baseline neuropsychiatric symptoms are effect modifiers in Ginkgo biloba extract (EGb 761) treatment of dementia with neuropsychiatric features. 1997;4(5):240-245. The effects of Ginkgo biloba extract (LI 1370) supplementation on activities of daily living in free living older volunteers: a questionnaire survey. Erectile dysfunction or ED occurs when a man experiences difficulty getting and keeping an erection. GINKGO (GING koh) is promoted for many conditions, such as memory loss, dementia, eye problems, poor blood circulation, and ringing in the ears. This includes EDTA, folic acid, GBL (gamma butyrolactone), GHB (gamma hydroxybutyrate), glutamine, hyssop oil, juniper, L-carnitine (levocarnitine), melatonin, rosemary, sage, wormwood, and others. Ginkgo biloba special extract LI 1370 improves dual-task walking in patients with MCI: a randomised, double-blind, placebo-controlled exploratory study. View abstract. View abstract. Bilateral haematoma after rhytidoplasty and blepharoplasty following chronic use of Ginkgo biloba. Taking ginkgo leaf extract multiple times per day might increase levels of talinolol. Yale SH, Glurich I. Am J Chin Med 2020;48(3):513-534 View abstract. View abstract. For improving cognitive function in healthy people, studies have used between 120 milligrams to 240 milligrams of the extract daily. Pennisi RS. Research: A 1999 study published in the journal Urology showed that DHEA treatment improved sexual performance. Dupuis C. Poison ivy. View abstract. Psychopharmacology (Berl) 2000;151:416-23. Clin Nucl Med. Suter, A., Niemer, W., and Klopp, R. A new ginkgo fresh plant extract increases microcirculation and radical scavenging activity in elderly patients. 2004;87(2):137-142. View abstract. Kose, K. and Dogan, P. Lipoperoxidation induced by hydrogen peroxide in human erythrocyte membranes. Meston CM, Rellini AH, Telch MJ. Ginkgo might also slow blood clotting. Invest Ophthalmol Vis Sci 2014;55(1):110-6. View abstract. Dietary supplement interactions with antiretrovirals: a systematic review. Ann Intern Med 2001;134:344. Radiat Res 1995;144:198-205. Polich J, Gloria R. Cognitive effects of a Ginkgo biloba/vinpocetine compound in normal adults: systematic assessment of perception, attention and memory. View abstract. Front Pharmacol 2022;13:821937. Jiang X, Blair EY, McLachlan AJ. Ginkgo does not seem to reduce the effects of simvastatin on cholesterol levels. Available for Android and iOS devices. View abstract. View abstract. J Bronchology Interv Pulmonol. Br J Plast Surg 2005;58:100-1. CNS Neurol Disord Drug Targets 2021 Feb 8. doi: 10.2174/1871527320666210208125524. Another is that it promotes blood flow through increasing the amount of nitric oxide. View abstract. While ginkgo biloba is generally considered safe when taken in moderate amounts, there are times when you should not take it. Some important interactions can include certain HIV medicines, seizure treatments, or anticoagulants (blood thinners) like warfarin. View abstract. Birks J, Grimley Evans J. Ginkgo biloba for cognitive impairment and dementia. J Sex Marital Ther 1999;25:2-5. All rights reserved. Association of Ginkgo biloba with intracerebral hemorrhage. View abstract. The efficacy of ginkgo for elderly people with dementia and age-associated memory impairment: new results of a randomized clinical trial. Pediatr Emerg Care 2003;19:206-10. Tabrizi R, Nowrouzi-Sohrabi P, Hessami K, et al. Six herbs for treating erectile dysfunction Dehydroepiandrosterone (DHEA) Horny goat weed (epimedium) Ginkgo L-arginine Red ginseng Yohimbine Erectile dysfunction is a condition that affects. Circ Cardiovasc Qual Outcomes 2010;3:41-7. Bal Dit, Sollier C., Caplain, H., and Drouet, L. No alteration in platelet function or coagulation induced by EGb761 in a controlled study. Recent innovations in medical treatments mean that there are now more medications available to reduce ED. Lancet 10-3-1998;352(9134):1145-1146. View abstract. Planta Med 1988;54:245-247. Ginkgo for memory enhancement: a randomized controlled trial. View abstract. View abstract. View abstract. Limitations of using a single postdose midazolam concentration to predict CYP3A-mediated drug interactions. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. View abstract. View abstract. But scientists believe it alter the levels of certain hormones in the body, which may in turn improve sexual performance. View abstract. Ginkgo seeds can be dangerous, especially when raw. Does Ginkgo biloba reduce the risk of cardiovascular events? Lebuisson DA, Leroy L, Rigal G. [Treatment of senile macular degeneration with Ginkgo biloba extract. Using different formulations together increases the risk of an overdose.
